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May 13, 2026Analytical Chemistry

Fluorescence-On Imaging of Golgiphagy with a Golgi Apparatus-Specific Metabolic Lipid Labeling Probe Fluorogenic to Lysosomal Acidity

Jipeng Yao Shixiong Wen Jiahuai Han Shoufa Han

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Key Points

The research aims to explore the detection of golgiphagy using a specific metabolic lipid labeling probe.
Utilized a novel Golgi-specific fluorescence probe, Golgi-proRed.
Focused on evaluating biological events related to golgiphagy.
Screened for agents inducing golgiphagy.
Successfully detected golgiphagy with Golgi-proRed during biological events.
Identified potential agents that initiate golgiphagy.

Implication

Demonstrates sensitive detection of golgiphagy in biological events, suggesting new screening for golgiphagy-inducing agents.

Abstract

. These results show the use of Golgi-proRed for sensitive detection of Golgiphagy in biological events and to screen Golgiphagy-inducing agents.

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Cite This Study

Yao et al. (2026) studied this question.

synapsesocial.com/papers/6a08093ca487c87a6a40b26a https://doi.org/10.1021/acs.analchem.5c07299

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