Malnutrition frequently complicates inflammatory bowel disease, arising from increased catabolism, nutrient loss, and decreased intake, leading to impaired outcomes. Nutritional intervention is vital for improving prognosis. A 71-year-old woman with ulcerative colitis, lost to follow-up, was admitted with severe malnutrition (body mass index 12.6 kg/m 2 ) and active disease. Infliximab was ineffective. Because of persistent inadequate intake and failed oral supplementation, exclusive enteral nutrition, thiamine, and intravenous multivitamins were started. Despite intervention, clinical deterioration progressed to pleural effusion, hemodynamic instability, and death. Multidisciplinary management is essential for addressing malnutrition and complex needs in patients with inflammatory bowel disease.
Yoshihara et al. (Thu,) studied this question.