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This review aims to explore the role of liquid biopsy in the diagnosis and monitoring of genitourinary cancers.

Role of liquid biopsy in genitourinary (GU) cancers

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This review aims to explore the role of liquid biopsy in the diagnosis and monitoring of genitourinary cancers.
Analyzed molecular components and isolation techniques of liquid biopsy platforms.
Evaluated clinical applications in prostate, bladder, renal cell, and testicular germ cell tumors.
Identified barriers to the routine adoption and outlined prospective study needs.
Liquid biopsy has shown potential for pre-biopsy risk stratification and monitoring treatment response.
Highlighted need for standardized procedures and management algorithms to implement liquid biopsy effectively.
Clinical utility remains a barrier to the widespread adoption of liquid biopsy in GU cancers.

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Narrative review examines liquid biopsy's utility in tracking genitourinary cancers and necessary advancements.

Kayaalp et al. (2026) studied this question.

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