Demonstrates total synthesis of verrucosamide, highlighting its configuration in peptide research.
-methylated 1,4-thiazepane scaffold. Starting from natural amino acids, this work culminates in a 27-step total synthesis of verrucosamide, establishing its absolute configuration and addressing a void in the total synthesis of the nonribosomal peptide bis-intercalators.
No takes yet. Share an insight, caveat, or question.
Zhang et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: