What question did this study set out to answer?

The study aimed to determine the clinical burden of influenza hospitalization and identify risk factors for severe outcomes in adults in Türkiye.

May 16, 2026MedicineOpen Access

Older adults bear the burden: risk factors for severe influenza outcomes among hospitalized adults in a 9-season multicenter active surveillance study

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Authors

LÖLale ÖzışıkHacettepe University MTMine Durusu TanrioverHacettepe University MOMurat OzdedeHacettepe University

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Implication

Multicenter active surveillance study identifies severe influenza outcomes among older adults and those with chronic conditions, highlighting vaccination importance.

Key Points

The study aimed to determine the clinical burden of influenza hospitalization and identify risk factors for severe outcomes in adults in Türkiye.
Multicenter active surveillance across Global Influenza Hospital Surveillance Network sites over 9 influenza seasons (2012–2024).
Included adults with laboratory-confirmed influenza infection screened within 72 hours of hospital admission.
Conducted multivariate logistic regression to identify independent risk factors for severe outcomes.
Among 351 adults with confirmed influenza, 21.1% required ICU admission and 11.1% died during hospitalization.
Additionally, diabetes increased ICU admission risk (aOR 1.91, 1.09–3.33) and chronic obstructive pulmonary disease predicted mechanical ventilation (aOR 3.13, 1.77–5.61).
Vaccination reduced the risk of ICU admission by 66% (aOR 0.34, 0.12–0.80).

Cite This Study

Özışık et al. (2026) studied this question.

synapsesocial.com/papers/6a080ae2a487c87a6a40ce35 https://doi.org/10.1097/md.0000000000048625

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Implication

Multicenter active surveillance study identifies severe influenza outcomes among older adults and those with chronic conditions, highlighting vaccination importance.

Older adults bear the burden: risk factors for severe influenza outcomes among hospitalized adults in a 9-season multicenter active surveillance study

Discussion

Member takes

Implication

Key Points

Cite This Study

Older adults bear the burden: risk factors for severe influenza outcomes among hospitalized adults in a 9-season multicenter active surveillance study

Discussion

Member takes

Implication

Key Points

Cite This Study

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