Background: Central pedicle mammoplasty (CPM) is an oncoplastic breast-conserving approach that allows for wide tumor removal while preserving the nipple-areolar complex and achieving favorable aesthetics. This study evaluated the safety, oncologic efficacy, complications, and cosmetic outcomes of CPM in early breast cancer patients with moderate to large, ptotic breasts. Patients and methods: A prospective study was conducted on 20 women with early-stage breast cancer who underwent CPM at Alexandria Main University Hospital (December 2023–March 2025). Demographics, tumor and surgical details, complications, and aesthetic outcomes were recorded. Wise pattern excision was used in all cases; 80% had contralateral symmetrization. Margins were assessed with intraoperative frozen sections, and aesthetics were evaluated by surgeons and patient surveys. Results: Median age was 51.5 years, with all patients overweight/obese (median BMI 34 kg/m²). Most had C-cup breasts (85%) and grade II ptosis (55%). Tumors averaged 2.5 cm, mainly in the upper outer quadrant. Negative margins were achieved intraoperatively in 95%; one patient required re-excision. Minor complications-seroma, hematoma, fat necrosis, or wound dehiscence-occurred in less than or equal to 15% and resolved conservatively. No major complications or recurrences were observed during a mean 9.5-month follow-up. Aesthetic results were excellent or good in 85%, mirrored by high patient satisfaction. Conclusion: CPM is a reliable oncoplastic option for breast conservation in selected patients, combining oncologic safety with strong cosmetic outcomes and low morbidity. Larger studies with longer follow-up are warranted to validate long-term results.
Eldamati et al. (Sun,) studied this question.