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May 1, 2026The Lancet Planetary HealthOpen Access

Physiological and biological response to heat exposure in pregnancy: a systematic review and meta-analysis

Ana Bonell A Qureshi Andreas D. Flouris Lydia Tsoutsoubi A N Sferruzzi-Perri Jai K Das Jane E Hirst Leonidas G Ioannou

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Key Points

Investigate the physiological and biological responses of pregnant women to heat exposure and its implications for maternal and fetal health.
Systematic review and meta-analysis of studies on pregnant women exposed to heat.
Data sourced from PubMed and Embase up to January 13, 2025.
Random-effects meta-analyses and meta-regression used to analyze associations between heat stress and physiological effects.
Maternal core temperature increased by 0.5°C with a 91% incidence across studies.
Fetal heart rate increased by 13 bpm (8.8-16.5) with a 78% incidence across studies.
Higher susceptibility to impaired uteroplacental blood flow was noted in women with hypertension or pre-eclampsia.

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Implication

Systematic review explores heat's effects on maternal and fetal physiology, indicating urgent need for further research.

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Cite This Study

Bonell et al. (2026) studied this question.

synapsesocial.com/papers/6a080b4ea487c87a6a40d831 https://doi.org/10.1016/j.lanplh.2026.101431

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