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April 22, 2022Current Forensic Science

Deaths Due to Cardiomyopathy of Unknown Etiology in Children andYoung Adults

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Key result

Cardiomyopathy of unknown etiology accounts for 14% of cardiomyopathy-related deaths in individuals under 40.

  • n=140

Why the study?

The study aimed to investigate the prevalence of deaths due to cardiomyopathies of unknown etiology in young subjects within a forensic pathology setting.

Population

140 decedents less than 40 years old with deaths due to cardiomyopathy

Design

Retrospective forensic autopsy study

Authors

SSSerenella SerinelliSUNY Upstate Medical UniversitySWSteven M. WhiteUK Centre for Ecology & HydrologyPAPonni ArunkumarNorthwestern University

Discussion

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Implication

Emphasizes need for comprehensive autopsy protocols in young sudden deaths; leaves open identification of novel etiologies.

Study Design

Type

Observational (n=140)

Multicenter

No

Structured PICO

P
Population
140 decedents less than 40 years old with deaths due to cardiomyopathy evaluated at the Cook County Medical Examiner’s Office in Chicago from January 2013 to June 2018.
O
Outcome
Prevalence of deaths due to cardiomyopathies of unknown etiologyhard clinical

In a forensic setting, 14% of sudden deaths due to cardiomyopathy in individuals under 40 years old have no identifiable underlying etiology, highlighting the need for thorough medical history and histological sampling.

Cite This Study

Serinelli et al. (2022) conducted an observational in Cardiomyopathy (n=140). Cardiomyopathy of unknown etiology accounted for 14% (20 of 140) of cardiomyopathy-related deaths among decedents under 40 years old in a forensic pathology setting.

synapsesocial.com/papers/6a081cca1e8b9db648ddf0fahttps://doi.org/10.2174/2666484401666220420105059

Topics

Cardiomyopathy
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1New insights into the pathology of inherited cardiomyopathy2005 · 152 citations
  2. 2Hypertrophic Cardiomyopathy2017 · 1,415 citations
  3. 3Obesity cardiomyopathy: a review of literature on clinical status and meta-analysis of diagnostic and clinical management2018 · 8 citations