July 8, 2022Cell Death and Disease130 citationsOpen Access

High levels of NRF2 sensitize temozolomide-resistant glioblastoma cells to ferroptosis via ABCC1/MRP1 upregulation

ISIzadora de Souza LMLinda Karolynne Seregni Monteiro CGCamila Banca Guedes

Key Points

Key points are not available for this paper at this time.

Abstract

is blocked by Erastin. Thus, ferroptosis induction could be an important therapeutic strategy to reverse drug resistance in gliomas with high NRF2 and ABCC1 expression.

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Souza et al. (2022) studied this question.

synapsesocial.com/papers/6a08246f1e8b9db648ddf3dd https://doi.org/10.1038/s41419-022-05044-9

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July 8, 2022Cell Death and Disease130 citationsOpen Access

High levels of NRF2 sensitize temozolomide-resistant glioblastoma cells to ferroptosis via ABCC1/MRP1 upregulation

ISIzadora de Souza LMLinda Karolynne Seregni Monteiro CGCamila Banca Guedes

Key Points

Key points are not available for this paper at this time.

Abstract

is blocked by Erastin. Thus, ferroptosis induction could be an important therapeutic strategy to reverse drug resistance in gliomas with high NRF2 and ABCC1 expression.

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Helpful

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View Full Paper

Cite This Study

Souza et al. (2022) studied this question.

synapsesocial.com/papers/6a08246f1e8b9db648ddf3dd https://doi.org/10.1038/s41419-022-05044-9

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