Key result
Point-of-care INR meters, when combined with a standardized education program, are safe, accurate, and effective for monitoring vitamin K antagonist therapy in children.
Why the study?
Are point-of-care INR monitors accurate, safe, and effective for measuring INR in children requiring vitamin K antagonists?
Are point-of-care INR monitors accurate, safe, and effective for measuring INR in children requiring vitamin K antagonists?
Point-of-care INR monitors are accurate, safe, and effective for managing vitamin K antagonist therapy in children when paired with standardized education.
Many children are surviving primary illnesses and now require thromboprophylaxis as a result of advances in management. Vitamin K antagonists are commonly prescribed to prevent or treat thrombosis. These agents are far more challenging to effectively manage in children. As a result of these challenges, frequent blood monitoring to measure international normalized ratio (INR) values is required. Point-of-care (POC) INR monitors use a capillary blood sample that has been expressed as a solution to improve effective management of vitamin K antagonist therapy. POC INR meters have been demonstrated to be accurate and precise in measuring INRs. Implementation of a standardized education program prior to patient use of POC meters results in differences between measured laboratory INRs and POC INR comparisons that meet criteria for clinical relevance. This indicates that POC INR meters are safe and effective for use in children.
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Bauman et al. (2008) conducted a review in Children requiring thromboprophylaxis with vitamin K antagonists. Point-of-care (POC) INR monitors vs. Laboratory INR measurement was evaluated on Accuracy and precision of INR measurement. Point-of-care INR meters, when combined with a standardized education program, are safe, accurate, and effective for monitoring vitamin K antagonist therapy in children.
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