Key result
Patient self-monitoring and self-adjustment of warfarin dosage achieved more prothrombin times within the therapeutic range compared to clinic-managed controls (88.6% vs 68.0%; P<.001).
Why the study?
Does patient self-monitoring and self-adjustment of warfarin dosage improve the percentage of prothrombin times within the therapeutic range in patients receiving oral anticoagulation?
Population
40 patients receiving oral anticoagulation at a tertiary medical institution
Comparison
Patient self-monitoring of prothrombin time… vs Matched control patients managed in an…
Design
Cohort
Follow-up
mean interval of 44.7 months for study patients and 42.5…
Authors
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Self-monitoring was associated with better INR control in this small cohort; leaves open confirmation in randomized trials before practice change.
Cohort (n=40)
No
Does patient self-monitoring and self-adjustment of warfarin dosage improve the percentage of prothrombin times within the therapeutic range in patients receiving oral anticoagulation?
Absolute Event Rate: 88.6% vs 68%
p-value: p=< .001
Long-term patient self-management of warfarin therapy significantly improves the proportion of time spent in the therapeutic range compared to standard clinic management, without increasing complications.
Jack Ansell (1995) conducted a cohort in Oral anticoagulation (n=40). Patient self-monitoring and self-adjustment of warfarin dosage vs. Clinic-managed oral anticoagulation was evaluated on Prothrombin times within the recommended therapeutic range (p=< .001). Patient self-monitoring and self-adjustment of warfarin dosage achieved more prothrombin times within the therapeutic range compared to clinic-managed controls (88.6% vs 68.0%; P<.001).
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