Key result
Apoptosis mediates the disappearance of infiltrated leukocytes and proliferated interstitial cells after MI, with apoptotic cells peaking at 2 days (5.3-6.9%) and decreasing by 4 weeks (0.5%).
Apoptosis plays an important role in the disappearance of infiltrated leukocytes and proliferated interstitial cells during the healing stage after myocardial infarction, which may have implications for postinfarct ventricular remodeling.
No takes yet. Share an insight, caveat, or question.
Apoptosis may clear post-MI leukocytes in rabbits; leaves open its modulation for human remodeling.
Takemura et al. (1998) studied Myocardial infarction (n=24). 30-minute occlusion of the left coronary artery followed by reperfusion vs. Different reperfusion durations (2 days, 2 weeks, 4 weeks) was evaluated on Frequency of interstitial cells with positive nick end labeling. Apoptosis mediates the disappearance of infiltrated leukocytes and proliferated interstitial cells after MI, with apoptotic cells peaking at 2 days (5.3-6.9%) and decreasing by 4 weeks (0.5%).
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: