Development of tCAP(N3): Affinity Peptide‐Aided, pH‐Triggered Strategy for Site‐Specific Native IgG Modification

)-Gly-Gly was site-selectively transferred onto Lys248, yielding divalently azidated IgG that can be further modified with DBCO compounds. The resulting antibody conjugates retained Fc receptor binding and antigen recognition comparable to the parent IgG.