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to release NO, leading to the self-propelled movement. It is found that the active movement of nanomotor promotes the AG-DMSNs ability to penetrate biofilm, thus achieving good biofilm clearance in vitro. More importantly, AG-DMSNs nanomotor can eliminate the biofilm of methicillin-resistant Staphylococcus aureus (MRSA) in vivo without causing damage to normal tissues. This nanomotor provides a new platform for the treatment of bacterial infections.
Zheng et al. (Mon,) studied this question.