Key result
Left ventricular hypertrophy is an increasingly recognized condition with important prognostic implications, driven by factors such as blood pressure, overweight, stress, and physical activity.
Echocardiography has revealed an epidemic of left ventricular hypertrophy, which carries important prognostic significance independent of standard risk factors.
LVH awareness may refine prognosis in practice; leaves open prospective trials on modifiable drivers.
The advent of echocardiography has added an important and sensitive tool for assessment of left ventricular hypertrophy (increased left ventricular mass). Recent echocardiographic studies in large population-based samples suggest an epidemic of left ventricular hypertrophy. Preliminary data suggesting important prognostic importance for such left ventricular hypertrophy (independent of standard risk factors) has fueled interest in the development, determinants, and other features of the hypertrophy. Hemodynamic and neurohumoral factors are the most prominent stimuli to adaptive (physiologic) myocardial hypertrophy, which can progress to maladaptive (pathologic) hypertrophy. The overall blood pressure experience, overweight, the cardiovascular response to recurrent psychosocial stress and physical activity level are four important correlates and potential determinants of left ventricular mass in various urban-suburban populations. Determination of the relative contributions and interrelations of these and other factors (such as heredity) to various forms of left ventricular hypertrophy found in various demographic groups warrants intensive investigation.
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Keurs et al. (2009) conducted a review in Left ventricular hypertrophy. Left ventricular hypertrophy is an increasingly recognized condition with important prognostic implications, driven by factors such as blood pressure, overweight, stress, and physical activity.
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