N6 -methyladenosine–Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression

Junge Deng; Jialiang Zhang; Ying Ye; Kaijing Liu; Lingxing Zeng; Jingyi Huang; Ling Pan; Mei Li; Ruihong Bai; Lisha Zhuang; Xudong Huang; Guandi Wu; Lusheng Wei; Yanfen Zheng; Jiachun Su; Shaoping Zhang; Rufu Chen; Dongxin Lin; Jian Zheng

doi:10.1158/0008-5472.can-21-0494

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Abstract

pseudogene results in increased translation of its protein-coding counterpart to promote Wnt signaling, which contributes to pancreatic cancer progression.

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Deng et al. (2021) studied this question.

synapsesocial.com/papers/6a08396d9a6c4ba6e61087fe https://doi.org/10.1158/0008-5472.can-21-0494

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N6 -methyladenosine–Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression

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Abstract

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Cite This Study

N6 -methyladenosine–Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression

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Abstract

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Cite This Study

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