Left ventricular unloading and survival outcomes in pediatric acute fulminant myocarditis patients receiving extracorporeal membrane oxygenation: A systematic review and meta-analysis

= .02). Other factors, such as age, gender, and cardiac arrest before ECMO, showed no significant associations with survival. Cumulative meta-analysis indicated an improving trend in survival over the years.ConclusionsThis meta-analysis suggests an association between ECMO and improved survival in children with AFM. While LV unloading may offer benefits, the retrospective nature of the included studies, along with potential confounding factors, necessitates cautious interpretation. Further well-designed prospective studies are required to establish its optimal role, indications, and timing in pediatric ECMO patients with AFM.