Why the study?
Although CCBs are often recommended as first-line treatment for hypertension, their effect on preventing cardiovascular events compared with other antihypertensive drug classes remains debated.
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Comparison
Calcium channel blockers vs other classes of antihypertensive drugs
Design
Updated systematic review
Effects of calcium channel blockers versus other antihypertensives on cardiovascular events remain unclear; leaves open optimal first-line therapy selection.
This is the first update of a review published in 2010. While calcium channel blockers (CCBs) are often recommended as a first-line drug to treat hypertension, the effect of CCBs on the prevention of cardiovascular events, as compared with other antihypertensive drug classes, is still debated.
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Zhu et al. (2021) studied this question.
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