Key result
Sex-specific cardiac aging mechanisms drive age-related heart disease susceptibility and necessitate tailored therapeutic approaches.
Why the study?
Understanding how sex-specific differences in cardiac aging are established and regulated remains limited, despite their contribution to age-related heart disease and differential stress responses.
Design
Review
Authors
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Sex differences in cardiac aging merit attention in clinical risk assessment; leaves open validation of sex-specific therapies in prospective trials.
This review highlights the mechanisms and implications of sex-specific cardiac aging and emphasizes the need for sex-specific therapeutic approaches in heart disease.
Yusifov et al. (2022) conducted a review in Cardiac aging. This review highlights the mechanisms of sex-specific cardiac aging, its role in age-related heart disease susceptibility, and the need for sex-specific therapeutic approaches.
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