Key result
Bariatric surgery was associated with a lower incidence of first-time fatal or nonfatal cardiovascular events compared to usual care (HR 0.67; 95% CI 0.54-0.83; P<0.001).
Why the study?
Does bariatric surgery reduce cardiovascular events and cardiovascular deaths in obese adults compared to usual care?
Population
4,047 obese adults (age 37 to 60 years, BMI ≥34 in men and ≥38 in women) in Sweden.
Comparison
Bariatric surgery vs Contemporaneously matched obese controls…
Design
Cohort, nonrandomized
Follow-up
median 14.7 years (range, 0-20 years)
Authors
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May inform bariatric surgery decisions in obese adults; leaves open causality without randomized confirmation.
Cohort (n=4,047)
Yes
Does bariatric surgery reduce cardiovascular events and cardiovascular deaths in obese adults compared to usual care?
Effect estimate: HR 0.67 (95% CI 0.54-0.83)
Absolute Event Rate: 9.9% vs 11.5%
p-value: p=<.001
Bariatric surgery is associated with a significant long-term reduction in cardiovascular deaths and first-time cardiovascular events compared to usual care in obese adults.
Sjöström et al. (2012) conducted a cohort in Obesity (n=4,047). Bariatric surgery vs. Usual care was evaluated on Total first time (fatal or nonfatal) cardiovascular events (myocardial infarction or stroke) (HR 0.67, 95% CI 0.54-0.83, p=<.001). Bariatric surgery was associated with a lower incidence of first-time fatal or nonfatal cardiovascular events compared to usual care (HR 0.67; 95% CI 0.54-0.83; P<0.001).
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