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Abstract Many natural products and biologically active compounds contain the dihydrofuran subunit. Molecules incorporating either 2‐substituted, 2,2‐disubstituted 2,3‐ or 2,5‐dihydrofurans are widespread in the literature and represent key “molecular building blocks”. The preparation of substituted dihydrofurans remains a current challenge in organic synthesis and this microreview details the various routes employed for their synthesis in the literature to the end of 2004. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
Kilroy et al. (Wed,) studied this question.