Key result
Saphenous-vein bypass grafting did not significantly change end-diastolic volume, end-systolic volume, or systolic ejection fraction compared to baseline, despite symptomatic improvement in 80%.
Why the study?
Does saphenous-vein bypass grafting improve resting ventricular performance in patients undergoing the procedure?
Population
40 patients undergoing saphenous-vein bypass grafting
Comparison
Saphenous-vein bypass grafting vs Pre-operative baseline
Design
Cohort
Authors
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No improvement in resting LV volumes or EF after saphenous-vein grafting; leaves open mechanisms of symptomatic benefit and requires prospective confirmation.
Observational (n=40)
Does saphenous-vein bypass grafting improve resting ventricular performance in patients undergoing the procedure?
Saphenous-vein bypass grafting improves symptoms and exercise performance but does not consistently improve resting left ventricular performance.
Hammermeister et al. (1974) conducted an observational in Coronary artery disease requiring bypass (n=40). Saphenous-vein bypass grafting vs. Baseline (before surgery) was evaluated on Resting ventricular performance, left ventricular volumes and ejection fraction. Saphenous-vein bypass grafting did not significantly change end-diastolic volume, end-systolic volume, or systolic ejection fraction compared to baseline, despite symptomatic improvement in 80%.
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