Key result
Higher corrected systolic inter-arm BP difference is linked to greater CAD severity.
Why the study?
Patients with severe atherosclerosis exhibit BP changes between arms, prompting investigation into the predictive value of interarm blood pressure difference for CAD severity.
Does inter-arm blood pressure difference predict coronary artery disease severity in patients undergoing coronary angiography?
Cross-Sectional (n=110)
Blinded outcome assessment
No
Does inter-arm blood pressure difference predict coronary artery disease severity in patients undergoing coronary angiography?
Inter-arm blood pressure difference is a simple, non-invasive clinical sign that correlates positively with angiographic coronary artery disease severity.
Answers are grounded in this paper and cite their sources.
Inter-arm BP difference may aid CAD severity evaluation in angiography patients; leaves open incremental value and prospective validation.
BACKGROUND: Patients with severe atherosclerosis have been found to exhibit considerable changes in blood pressure (BP) between arms. The objective of our study was to investigate the predictive value of interarm blood pressure difference (IABPD) for coronary artery disease (CAD) severity. METHODS: It was a cross-sectional study conducted in the Department of Cardiology, Chittagong Medical College Hospital, Chattogram from May 2020 to November 2020. The study conveniently selected 110 individuals who visited the department for a coronary angiography during the study period. The BP of both arms were synchronously measured 1-2 days before the coronary angiography and IABPD were calculated. After coronary angiography, two blinded interventional cardiologists visually estimated the amount of coronary artery obstruction and determined the Gensini score. RESULTS: Among the participants, more than three-fourths of the patients were above 50 years of age (64.66%), and the majority were male (86.67%). 14.7% of participants had no occlusion in their coronary artery, 38.0% of participants had insignificant occlusion, 26.7% participants had mild occlusion, 10.3% participants had moderate occlusion, 3.3% participants had significant occlusion and 6.0% participants had total occlusion. Corrected pulse IABPD (cIABPDpulse) showed the greatest area under the receiver operating characteristic curve (0.73) for predicting a high Gensini score (>median). Multiple regression analysis revealed a significant relationship between corrected systolic IABPD (cIABPDsys) and the Gensini score (B=0.057, p<0.001). CONCLUSION: The differences in BP between the arms were found to be having a strong positive correlation with CAD severity.
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Das et al. (2022) conducted a cross-sectional in Coronary artery disease (n=110). Inter-arm blood pressure difference (IABPD) was evaluated on Coronary artery disease severity (Gensini score) (B=0.057, p=<0.001). Corrected systolic inter-arm blood pressure difference showed a significant positive relationship with coronary artery disease severity as measured by the Gensini score (B=0.057, p<0.001).
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