Key result
Apical ballooning syndrome demonstrates an ~11% four-year recurrence rate despite normal survival.
Why the study?
Apical ballooning syndrome is a recently described acute cardiac syndrome with uncertain etiology and prognosis.
Cohort (n=100)
Apical ballooning syndrome has a notable recurrence rate of 11.4% over 4 years, though long-term survival remains similar to the general matched population.
OBJECTIVES: This study sought to assess the long-term prognosis of patients with apical ballooning syndrome (ABS). BACKGROUND: Apical ballooning syndrome is a recently described acute cardiac syndrome of uncertain etiology and prognosis. METHODS: We retrospectively identified 100 unselected patients with a confirmed diagnosis of ABS by angiography. Recurrences of ABS and mortality were recorded. RESULTS: Over a mean follow-up of 4.4 +/- 4.6 years, 31 patients continued to have episodes of chest pain and 10 patients had recurrence of ABS, for a recurrence rate of 11.4% over the first 4 years. Seventeen patients died in 4.7 +/- 4.8 years of follow-up. There was no difference in survival or in cardiovascular survival to an age- and gender-matched population. CONCLUSIONS: The recurrence rate for ABS was 11.4% over 4 years after initial presentation. Recurrence of chest pain is common. Four-year survival was not different from that in an age-matched and gender-matched population.
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Elesber et al. (2007) conducted a cohort in Apical ballooning syndrome (n=100). Apical ballooning syndrome was associated with an 11.4% recurrence rate over 4 years, while four-year survival did not differ from an age- and gender-matched population.
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