The Potential Importance of CXCL1 in the Physiological State and in Noncancer Diseases of the Cardiovascular System, Respiratory System and Skin

Jan Korbecki; Agnieszka Maruszewska; Mateusz Bosiacki; Dariusz Chlubek; Irena Baranowska‐Bosiacka

doi:10.3390/ijms24010205

December 22, 2022International Journal of Molecular SciencesOpen Access

The Potential Importance of CXCL1 in the Physiological State and in Noncancer Diseases of the Cardiovascular System, Respiratory System and Skin

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Key Points

To examine the physiological functions of CXCL1 and evaluate its role in noncancer pathologies affecting the cardiovascular, respiratory, and integumentary systems.
Synthesized evidence concerning the biological activity of CXCL1 in healthy tissue states and noncancer conditions.
Characterized the mechanisms by which CXCL1 regulates vascular processes, focusing on angiogenesis and arteriogenesis.
CXCL1 exerts meaningful regulatory effects on vascular physiology, particularly by promoting new vessel growth through angiogenesis.
The chemokine contributes to the remodeling and enlargement of existing vessels via arteriogenesis.
CXCL1 signaling is implicated in maintaining baseline physiological balance as well as driving noncancer disease states across cardiovascular, respiratory, and skin tissues.

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Implication

Reviews the physiological functions and noncancer pathological roles of CXCL1, highlighting its regulatory effects on angiogenesis and arteriogenesis.

Abstract

). Additionally, the significance of CXCL1 is described in vascular physiology, such as the effects of CXCL1 on angiogenesis and arteriogenesis.

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Korbecki et al. (2022) studied this question.

synapsesocial.com/papers/6a0898b6280cd4e998e8d01d https://doi.org/10.3390/ijms24010205

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The Potential Importance of CXCL1 in the Physiological State and in Noncancer Diseases of the Cardiovascular System, Respiratory System and Skin

Key Points

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Implication

Abstract

Discussion

Cite This Study

The Potential Importance of CXCL1 in the Physiological State and in Noncancer Diseases of the Cardiovascular System, Respiratory System and Skin

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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