Key result
This review highlights the molecular and cellular mechanisms of atrial fibrosis, including matrix metalloproteinases and profibrotic signals, and its relationship with atrial fibrillation.
This review summarizes the molecular and cellular mechanisms of atrial fibrosis and its role as a substrate for atrial fibrillation.
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Does not yet guide AF therapy; leaves open targeted antifibrotic strategies for future trials.
Goudis et al. (2012) conducted a review in Atrial fibrillation and atrial fibrosis. This review highlights the molecular and cellular mechanisms of atrial fibrosis, including matrix metalloproteinases and profibrotic signals, and its relationship with atrial fibrillation.
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