Why the study?
The prognostic role of atrial fibrillation and its association with mortality in patients with transthyretin amyloid cardiomyopathy were not well established.
Does atrial fibrillation predict all-cause mortality in patients with transthyretin amyloid cardiomyopathy?
Population
22 patients with confirmed ATTR-CM
Comparison
AF vs no AF
Design
Cohort study
Follow-up
Mean 18.2 ± 6.8 months
Authors
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AF not independently tied to mortality in ATTR-CM; leaves open whether rhythm control alters outcomes in this population.
Does atrial fibrillation predict all-cause mortality in patients with transthyretin amyloid cardiomyopathy?
In patients with ATTR-CM, atrial fibrillation is a marker of more advanced disease severity rather than an independent predictor of all-cause mortality.
Penate et al. (2026) studied this question.
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