Key result
AV junction ablation in patients with drug-refractory atrial fibrillation and baseline LVEF <50% significantly improved LVEF from 32% to 45% at 216 days (P<0.001).
Why the study?
Does radiofrequency ablation of the atrioventricular junction improve left ventricular function in patients with drug refractory atrial fibrillation?
Observational (n=29)
Does radiofrequency ablation of the atrioventricular junction improve left ventricular function in patients with drug refractory atrial fibrillation?
p-value: p=< 0.001
Atrioventricular junction ablation for drug-refractory atrial fibrillation improves long-term systolic and diastolic function in patients with baseline LV dysfunction without adversely affecting normal LV function.
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May support AV junction ablation for LVEF gains in drug-refractory AF with reduced EF; hypothesis-generating, needs RCTs before practice change.
Edner et al. (1995) conducted an observational in drug refractory atrial fibrillation (n=29). Radiofrequency ablation of the atrioventricular junction was evaluated on Left ventricular ejection fraction and early filling deceleration times (Edec) (p=< 0.001). AV junction ablation in patients with drug-refractory atrial fibrillation and baseline LVEF <50% significantly improved LVEF from 32% to 45% at 216 days (P<0.001).
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