Early rhythm control in patients with acute decompensated heart failure: results from the CYCLE cohort study

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  Figure 1. Associations of use of early rhythm control (A) and successful early rhythm control (B) with all-cause mortality. Kaplan–Meier estimates were used to illustrate cumulative all-cause mortality over time. Multivariable Cox regression analyses of early rhythm control and successful early rhythm control associated with all-cause mortality, adjusted for age, sex, and lactate levels >2.2 mmol/L. Results are shown as adjusted HRs with 95% CI and illustrated in a forest plot (C). Multivariable logistic regression analyses identifying associations between clinical factors and (D) the use of early rhythm control and (E) successful rhythm control, defined as sinus rhythm at discharge. Results are shown as adjusted ORs with 95% CI and illustrated in a forest plot. Abbreviations: BMI, body mass index; CI, confidence interval; OR, odds ratio; CRP, C-reactive protein; HF, heart failure; HR, hazard ratio; i.v., intravenously; NT-proBNP, N-terminal pro-B-type natriuretic peptide; RAASi, renin–angiotensin–aldosterone system inhibitors.