What question did this study set out to answer?

To assess the effect of propranolol hydrochloride compared to placebo on mortality in patients enrolled shortly after an acute myocardial infarction.

November 6, 1981JAMA

The beta-blocker heart attack trial. beta-Blocker Heart Attack Study Group

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Implication

Randomized double-blind trial shows a 26% mortality reduction with propranolol in post-infarction patients, indicating significant survival benefits from early beta-blocker therapy.

Key Points

To assess the effect of propranolol hydrochloride compared to placebo on mortality in patients enrolled shortly after an acute myocardial infarction.
Multicenter, randomized, double-blind clinical trial.
Evaluated propranolol hydrochloride versus placebo in patients enrolled shortly after an acute myocardial infarction.
Patients receiving propranolol hydrochloride experienced a 26% lower mortality rate compared to the placebo control group.
The trial was terminated prematurely on the recommendation of the Policy and Data Monitoring Board due to demonstrated efficacy.

Cite This Study

A 1981 study studied this question.

synapsesocial.com/papers/6a08caee96b78901e666c20a https://doi.org/10.1001/jama.246.18.2073

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Bookmark

Implication

Randomized double-blind trial shows a 26% mortality reduction with propranolol in post-infarction patients, indicating significant survival benefits from early beta-blocker therapy.

The beta-blocker heart attack trial. beta-Blocker Heart Attack Study Group

Discussion

Member takes

Implication

Key Points

Cite This Study

The beta-blocker heart attack trial. beta-Blocker Heart Attack Study Group

Discussion

Member takes

Implication

Key Points

Cite This Study

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