Key result
General anaesthesia linked to ~97% faster room-to-incision intervals vs epidural top-up but worse neonatal outcomes.
Why the study?
Does general anaesthesia compared to epidural top-up reduce operating room-to-incision interval and affect neonatal outcomes in women undergoing category-1 caesarean section?
Population
677 women undergoing category-1 emergency caesarean section
Comparison
General anaesthesia, spinal anaesthesia, or… vs Epidural top-up
Design
Cohort
Follow-up
short term (neonatal)
Authors
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General anaesthesia may speed category-1 caesarean incision yet worsen neonatal outcomes; leaves open optimal choice pending randomized data.
Cohort (n=677)
Does general anaesthesia compared to epidural top-up reduce operating room-to-incision interval and affect neonatal outcomes in women undergoing category-1 caesarean section?
Effect estimate: HR 1.97 (95% CI 1.60-2.44)
Absolute Event Rate: 6% vs 11%
p-value: p=< 0.0001
While general anaesthesia provides the fastest operating room-to-incision interval for category-1 caesarean sections, it is associated with worse short-term neonatal outcomes.
Palmer et al. (2018) conducted a cohort in Category-1 caesarean section (n=677). General anaesthesia vs. Epidural top-up was evaluated on Operating room-to-incision interval (HR 1.97, 95% CI 1.60-2.44, p=< 0.0001). General anaesthesia was associated with the most rapid operating room-to-incision interval compared to epidural top-up (HR 1.97; 95% CI 1.60-2.44; p<0.0001), but worse short-term neonatal outcomes.
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