Key result
Among Indian patients with hypertrophic cardiomyopathy, 45.3% had no sudden cardiac death risk factors, while 26.5% had apical HCM and 6% had a family history of sudden cardiac death.
Why the study?
Patients with HCM have an increased risk of SCD, but there are very few studies from India evaluating the prevalence of established SCD risk factors in this population.
Observational (n=117)
No
In a South Indian cohort of HCM patients, there is a high prevalence of apical HCM and a relatively low prevalence of familial HCM and family history of SCD.
BACKGROUND Cardio-Myopathy (HCM) is the commonest genetic cardiovascular . Patients with HCM are at higher risk for sudden cardiac death (SCD) than general population. There are some risk factors which identify patients with risk for SCD among HCM patients. There are very few studies from India the prevalence of SCD risk factors among HCM patients. Studies have risk factors for sudden cardiac death (SCD) in patients with hypertrophic (HCM). We aimed to study the prevalence of established risk for SCD among Indian patients with HCM. prospective registry for patients between 12 years and 85 years of age with HCM started in Calicut Government Medical College, South India, from Jan 2016. patients were assessed in detail with history, clinical examination, ECG, , 24 hour Holter and treadmill test. 117 unrelated patients with HCM were studied. Mean age of the patients was 58 ± 11.5 years. 45.3% had no SCD risk factors as per AHA / ACC 2011 criteria for . Rest of the patients had SCD risk factors as follows - family history of SCD 6 %, NSVT in Holter in 18.8 %, unexplained syncope in previous six months in 18.8 %, abnormal BP response to treadmill exercise (9.8 %), maximum LV ≥30 mm in 9.4 % and LVOT gradient ≥ 30 in 28 (24 %). Prevalence of HCM was 26.5 %. is high prevalence of apical HCM in India. Prevalence of conventional risk is low in Apical HCM. Prevalence of familial HCM and family history of SCD low. Prevalence of other risk factors is comparable to studies from elsewhere.
No takes yet. Share an insight, caveat, or question.
Valappil et al. (2020) conducted an observational in Hypertrophic Cardiomyopathy (n=117). Among Indian patients with hypertrophic cardiomyopathy, 45.3% had no sudden cardiac death risk factors, while 26.5% had apical HCM and 6% had a family history of sudden cardiac death.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: