Key result
Mitral valve repair in dogs is linked to improved QoL for up to 12 months.
Why the study?
To determine changes in health-related quality of life up to 12 months after surgery in dogs with myxomatous mitral valve disease undergoing mitral valve repair.
Does mitral valve repair improve health-related quality of life in dogs with myxomatous mitral valve disease?
Cohort (n=54)
No
Does mitral valve repair improve health-related quality of life in dogs with myxomatous mitral valve disease?
Mitral valve repair significantly improves owner-assessed health-related quality of life in dogs with myxomatous mitral valve disease for up to 12 months post-surgery.
May support surgical consideration for quality of life in dogs; leaves open need for randomized trials before practice change.
OBJECTIVE To determine changes in health-related quality of life up to 12 months after surgery in dogs with myxomatous mitral valve disease that undergo mitral valve repair. ANIMALS 54 dogs that underwent mitral valve repair at a United Kingdom referral hospital. PROCEDURES Health-related quality of life was assessed with a previously validated, owner-completed questionnaire before and 1, 3, 6, and 12 months after surgery. Results There was a significant decrease in total score (corresponding to reduced negative impact of cardiac disease on quality of life) between the preoperative timepoint and all postoperative timepoints. A significant decrease in total score was also demonstrated between the 1- and 3-month timepoints, but no additional significant changes in total score between adjacent timepoints were identified beyond 3 months after surgery. Significant improvements in individual question scores were found up to 12 months after surgery. CLINICAL RELEVANCE Health-related quality of life was significantly improved following mitral valve repair in dogs with myxomatous mitral valve disease and this improvement persisted for up to a year after surgery. These results may be useful when counseling owners of dogs considered candidates for this procedure.
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Pennington et al. (2022) conducted a cohort in myxomatous mitral valve disease (n=54). Mitral valve repair vs. Preoperative baseline was evaluated on Changes in health-related quality of life total score. Mitral valve repair in dogs with myxomatous mitral valve disease significantly improved health-related quality of life scores for up to 12 months postoperatively compared to baseline.
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