Key result
Mitral valve surgery is linked to a ~44% improvement in quality of life at two weeks.
Why the study?
Mitral valve disease affects physical and mental health, but psychological aspects like quality of life, anxiety, and depression are often overlooked despite surgery potentially enhancing mental health.
Does mitral valve repair/replacement surgery improve quality of life, anxiety, and depression in patients with mitral valve disease?
Observational (n=60)
No
Does mitral valve repair/replacement surgery improve quality of life, anxiety, and depression in patients with mitral valve disease?
Absolute Event Rate: 83.83% vs 58.167%
Mitral valve repair or replacement surgery is associated with significant short-term improvements in quality of life, anxiety, and depression.
Short-term QoL gains after mitral valve surgery should not yet change practice; leaves open need for RCTs to confirm causality and durability.
Background: Mitral valve disease significantly impacts physical and mental health. Psychological aspects like quality of life (QoL), anxiety, and depression are often overlooked. Studies indicate that surgical interventions can greatly enhance mental health, which is crucial for recovery and overall well-being. Aim: To evaluate the QoL, anxiety, and depression in patients before and 2 weeks after undergoing mitral valve repair/replacement surgery. Materials and Methods: This analytical, longitudinal study was conducted in a tertiary care hospital in Maharashtra. Using purposive sampling, patients undergoing mitral valve repair/replacement surgeries who met inclusion criteria and provided informed consent were included in the study. They were interviewed using a sociodemographic proforma, clinical questionnaire, Euro Qol 5D-5L (EQ-5D-5L), and Hospital Anxiety and Depression Scale before and 2 weeks after surgery. Additional information was obtained from the patient’s case files. Results: This study included 60 patients. Before surgery, 73.33% reported decreased sleep, 63.33% reported decreased appetite, the mean scores for QoL assessment were 58.167, 16.67% of participants were borderline depressed, 13.33% of participants were depressed, 20% participants were borderline anxious, and 21.67% of participants were anxious. Two weeks after surgery, 95% of participants reported normal sleep and appetite, and QoL mean scores improved to 83.83. 90% of participants reported no symptoms of depression, and 91.67% of participants reported no anxiety symptoms. Conclusion: Mitral valve repair/replacement surgery is associated with significant alleviation of anxiety and depression symptoms and improves QoL.
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Janiani et al. (2026) conducted an observational in Mitral valve disease (n=60). Mitral valve repair/replacement surgery vs. Before surgery (baseline) was evaluated on Quality of life (QoL) mean score. Mitral valve repair/replacement surgery improved mean quality of life scores from 58.17 to 83.83 at 2 weeks post-surgery, with 90% of patients reporting no symptoms of depression.
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