Key result
Digitalis remains an effective component of individualized combination therapy for HF.
This historical and physiological review argues that digitalis remains a valuable component of individualized, combined medical therapy for heart failure, particularly in severe cases, due to its unique ability to increase contractility while reducing myocardial oxygen consumption.
May support digitalis in severe HF regimens; leaves open prospective RCTs for confirmation.
In Mexico, digitalis was known since the 16th century and was used to treat patients with bloating, and it was not until the 20th century that it began to be used as a medicine for heart failure. In conjunction with diuretics. Digitalis was later used in combination individualized with the new medications, for this purpose and research has shown that the combination of medications on an individualized basis is what is currently successfully available for the medical treatment of heart failure.
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José Fernando Guadalajara‐Boo (2024) conducted a review in Heart failure. Digitalis was evaluated. Digitalis, known in Mexico since the 16th century, is currently used successfully in individualized combination therapy for the medical treatment of heart failure.
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