December 7, 1999Annals of Internal Medicine
Systemic Amyloidosis Presenting with Angina Pectoris
Key result
Systemic amyloidosis can present as angina pectoris with coronary flow reserve abnormalities despite normal coronary angiograms, as observed in all 5 patients in this series.
Population
5 patients who presented with angina pectoris and normal coronary angiogram as the initial manifestation of…
Design
Case_series
Authors
Discussion
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Implication
May prompt consideration of amyloidosis in angina with normal angiograms and reduced flow reserve; leaves open need for prospective validation.
Study Design
Type
Case Report (n=5)
Multicenter
No
Structured PICO
P
Population
5 patients who presented with angina pectoris and normal coronary angiogram as the initial manifestation of systemic amyloidosis.
O
Outcome
Endothelial-dependent and endothelial-independent coronary flow reservesurrogate
Cardiac amyloidosis can present as angina pectoris associated with coronary flow reserve abnormalities despite normal epicardial coronary angiograms.
Cite This Study
Suwaidi et al. (1999) conducted a case report in Systemic amyloidosis (n=5). Systemic amyloidosis can present as angina pectoris with coronary flow reserve abnormalities despite normal coronary angiograms, as observed in all 5 patients in this series.