Key result
Elevated cardiac troponin occurs in diverse non-MI conditions including diabetes, hypertension, cardiomyopathies, and arrhythmias.
This review highlights the diverse pathological and false-positive mechanisms that can lead to elevated cardiac troponins in the absence of acute myocardial infarction, aiding in accurate diagnostic interpretation.
May prompt broader differentials for troponin elevation; extends non-MI associations but leaves open validated interpretive algorithms.
This article proceeds with a discussion of the causes and mechanisms of an elevation in cardiac troponins in pathological conditions not associated with acute myocardial infarction. The second part of the article discusses the causes and mechanisms of cardiac troponins elevation in diabetes mellitus, arterial hypertension, hereditary cardiomyopathies, cardiac arrhythmias (atrial fibrillation, supraventricular tachycardia), acute aortic dissection, and diseases of the central nervous system (strokes, subarachnoidal hemorrhage). The final chapter of this article discusses in detail the false-positive causes and mechanisms of elevated cardiac troponins.
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Aleksey M. Chaulin (2021) conducted a review in Elevated cardiac troponins not associated with myocardial infarction. Cardiac troponin elevation occurs in various non-myocardial infarction conditions, including diabetes, hypertension, cardiomyopathies, arrhythmias, aortic dissection, and central nervous system diseases.
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