Key result
Emotional Takotsubo triggers linked to ~9% long-term mortality, lower than physical or no triggers.
Why the study?
Takotsubo syndrome is usually triggered by a stressful event, and because the type of trigger appears to influence outcomes, its clinical implications warrant separate evaluation.
Does the type of trigger (emotional, physical, or none) affect clinical outcomes and mortality in patients with Takotsubo syndrome?
Population
2482 patients with Takotsubo syndrome in the GEIST registry
Comparison
Physical trigger vs emotional trigger vs no trigger
Design
Multicenter registry study
Authors
Loading...
Emotional triggers identify lower-risk Takotsubo patients but should not alter care; leaves open whether trigger-specific interventions improve outcomes.
Observational (n=2,482)
Yes
Does the type of trigger (emotional, physical, or none) affect clinical outcomes and mortality in patients with Takotsubo syndrome?
p-value: p=<0.001
Patients with Takotsubo syndrome triggered by emotional events have significantly lower rates of adverse in-hospital events and long-term mortality compared to those with physical or no identifiable triggers.
Pätz et al. (2023) conducted an observational in Takotsubo syndrome (n=2,482). Emotional trigger vs. Physical trigger and no trigger was evaluated on Long-term mortality (p=<0.001). Emotional triggers in Takotsubo syndrome were associated with significantly lower long-term mortality (8.5%) compared to physical (21.6%) or no triggers (14.4%; P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: