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March 5, 2015Circulation Arrhythmia and Electrophysiology

Five-Year Follow-Up After Catheter Ablation of Persistent Atrial Fibrillation Using the Stepwise Approach and Prognostic Factors for Success

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Key result

Stepwise catheter ablation for persistent AF achieves a ~20% single-procedure success rate at five years.

  • n=493

Population

493 patients with persistent atrial fibrillation who underwent de novo catheter ablation using the stepwise…

Design

Cohort

Follow-up

mean 59±16 months

Authors

DSDoreen SchreiberKlinik HirslandenTRThomas RostockElectrophysiologyMFMax FröhlichUniversität Hamburg

Discussion

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Implication

Limited long-term success after stepwise ablation for persistent AF warrants caution in patient selection; leaves open whether alternative strategies improve outcomes in randomized trials.

Study Design

Type

Cohort (n=493)

Structured PICO

P
Population
493 patients with persistent atrial fibrillation who underwent de novo catheter ablation using the stepwise approach
I
Intervention
Catheter ablation using the stepwise approach aiming at atrial fibrillation termination
O
Outcome
5-year single and multiple procedure success (freedom from arrhythmia recurrence)

Catheter ablation of persistent atrial fibrillation using a stepwise approach provides limited long-term freedom from arrhythmias, often requiring multiple procedures.

Cite This Study

Schreiber et al. (2015) conducted a cohort in Persistent atrial fibrillation (n=493). Catheter ablation using the stepwise approach was evaluated on 5-year single procedure success. Catheter ablation of persistent atrial fibrillation using a stepwise approach yielded a 5-year single-procedure success rate of 20.1% and a multiple-procedure success rate of 55.9%.

synapsesocial.com/papers/6a090899bee8d5ab8a92db81https://doi.org/10.1161/circep.114.001672

Topics

Persistent AF managementAtrial fibrillationAF ablation outcomesAnticoagulation in AF
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Importance of Sinus Rhythm as Endpoint of Persistent Atrial Fibrillation Ablation2012 · 51 citations
  2. 2State of the Art: Catheter Ablation of Atrial Fibrillation2008 · 91 citations
  3. 3Long-Term Outcome After Successful Catheter Ablation of Atrial Fibrillation2010 · 239 citations
  4. 4Atrial fibrillation catheter ablation in females: same hardware, different findings2011 · 11 citations
  5. 5Characterization of Conduction Recovery Across Left Atrial Linear Lesions in Patients with Paroxysmal and Persistent Atrial Fibrillation2006 · 113 citations