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March 1, 1980Heart532 citationsOpen Access

Non-invasive assessment of aortic stenosis by Doppler ultrasound.

LHLiv HatleBAB. A. J. AngelsenATArve Tromsdal

Key Result

Doppler ultrasound measurement of peak pressure drop was within 25% of catheterisation values in 17 of 18 patients under 50 years, but significantly underestimated in one-third of patients over 50.

Study Design

Type

Observational (n=63)

Structured PICO

Does Doppler ultrasound accurately measure peak pressure drop compared to catheterisation in patients with aortic stenosis?

P
Population
63 patients with aortic stenosis
I
Intervention
Doppler ultrasound to measure peak pressure drop across the aortic valve
C
Comparator
Catheterisation
O
Outcome
Peak pressure drop across the aortic valvesurrogate

Doppler ultrasound provides a reproducible and reasonably accurate non-invasive estimation of peak pressure drop in younger patients with aortic stenosis, though it frequently underestimates severity in older patients.

Limitations

  • In patients over 50 years Doppler signals from the aortic jet were more difficult to obtain, and pressure drop was significantly underestimated in one-third.
  • Angle dependence can underestimate maximal velocity and pressure drop
  • Doppler signals from the aortic jet were more difficult to obtain in patients over 50 years

Abstract

The peak pressure drop across the aortic valve in aortic stenosis has been measured by Doppler ultrasound. Maximum velocity in the Doppler signal from the aortic jet was recorded using a maximum frequency estimator. With an angle close to zero between ultrasound beam and maximal velocity in the jet, peak pressure drop can be calculated from the maximal velocity measured; a larger angle will underestimate maximal velocity and pressure drop. In 57 of 63 patients with aortic stenosis, the aortic jet could be reached by the ultrasound beam and, in 37 of these, peak pressure drop by ultrasound was compared with that obtained at catheterisation. In patients less than 50 years of age the aortic jet was easy to find, the measurement was reproducible, and underestimation of the pressure drop obtained at catheterisation was within 25 per cent in 17 of 18 patients. In patients over 50 years Doppler signals from the aortic jet were more difficult to obtain, and pressure drop was significantly underestimated in one-third, but time of maximum velocity in systole could indicate whether moderate or severe aortic stenosis was present.

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Cite This Study

Hatle et al. (1980) conducted an observational in Aortic stenosis (n=63). Doppler ultrasound vs. Catheterisation was evaluated on Peak pressure drop across the aortic valve. Doppler ultrasound measurement of peak pressure drop was within 25% of catheterisation values in 17 of 18 patients under 50 years, but significantly underestimated in one-third of patients over 50.

synapsesocial.com/papers/6a09093529af591ab7017362https://doi.org/10.1136/hrt.43.3.284
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