May 29, 2026Journal of the American College of Cardiology
Prediction of the severity of aortic stenosis by Doppler aortic valve area determination: Prospective Doppler-catheterization correlation in 100 patients
Key result
Doppler echo reliably estimates AS severity, correlating strongly with invasive catheterization.
- r = 0.86
- n=100
Why the study?
The study was conducted to identify Doppler variables predictive of aortic stenosis severity and compare Doppler- and catheterization-derived aortic valve areas.
Does Doppler echocardiography accurately estimate the severity of aortic stenosis compared to invasive cardiac catheterization in patients with aortic stenosis?
Population
100 patients with aortic stenosis undergoing clinically indicated cardiac catheterization
Comparison
Doppler echocardiography vs cardiac catheterization
Design
Prospective observational correlation study
Authors
Discussion
Loading...
Member takes
Implication
Supports Doppler continuity equation for noninvasive aortic stenosis assessment; leaves open need for randomized trials before replacing catheterization.
Key Points
- The study aims to evaluate the effectiveness of Doppler aortic valve area determination in predicting the severity of aortic stenosis.
- Prospective design involving correlation between Doppler measurements and catheterization results in 100 patients.
- Assessment of aortic valve area using Doppler echocardiography before catheterization.
- Doppler aortic valve area measurement accurately predicts severity of aortic stenosis in 95% of cases, with a significant correlation coefficient (r=0.85, p<0.001).
- Thirteen patients exhibited discordant classifications between Doppler and catheterization results, showcasing the clarity in Doppler predictions.
Study Design
Type
Observational (n=100)
Structured PICO
Does Doppler echocardiography accurately estimate the severity of aortic stenosis compared to invasive cardiac catheterization in patients with aortic stenosis?
P
Population
100 patients with aortic stenosis undergoing clinically indicated cardiac catheterization
I
Intervention
Two-dimensional and Doppler echocardiography
C
Comparator
Cardiac catheterization (Gorlin equation)
O
Outcome
Correlation between Doppler-derived and catheterization-derived aortic valve areas and gradientssurrogate
Main Result
Effect estimate: r = 0.86
Doppler echocardiography provides a reliable noninvasive estimation of aortic stenosis severity, correlating well with invasive catheterization measurements.
Cite This Study
Oh et al. (1988) conducted an observational in Aortic stenosis (n=100). Doppler echocardiography vs. Cardiac catheterization was evaluated on Correlation between Doppler-derived and catheterization-derived mean gradient (r = 0.86). Doppler echocardiography provided reliable noninvasive estimation of aortic stenosis severity, with Doppler-derived mean gradient correlating well with catheterization (r = 0.86).