Why the study?
Does the incidence and prognosis of high-degree atrioventricular block in acute coronary syndrome patients improve over time?
Population
18,717 acute coronary syndrome patients from the multicenter ACSIS registry
Comparison
Late period (2013–2021) vs Early period (2000–2010)
Design
Cohort
Follow-up
1 year
Key result
The late period (2013-2021) compared to the early period (2000-2010) was associated with lower 1-year mortality among ACS patients with high-degree AV block (26.1% vs 36.5%, P=0.022).
Authors
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May support expectations of better outcomes in current ACS-HDAVB practice; leaves open identification of key contributing factors.
Observational (n=18,717)
Yes
Does the incidence and prognosis of high-degree atrioventricular block in acute coronary syndrome patients improve over time?
The incidence and mortality of high-degree atrioventricular block complicating acute coronary syndrome have significantly decreased over the last two decades.
Absolute Event Rate: 26.1% vs 36.5%
p-value: p=0.022
Tal et al. (2025) conducted an observational in Acute coronary syndrome with high-degree atrioventricular block (n=18,717). Late period (2013-2021) vs. Early period (2000-2010) was evaluated on 1-year mortality (p=0.022). The late period (2013-2021) compared to the early period (2000-2010) was associated with lower 1-year mortality among ACS patients with high-degree AV block (26.1% vs 36.5%, P=0.022).