Key result
Insular cortex derangement disrupts autonomic cardiac regulation and can lead to SCD.
This review highlights the critical role of the insular cortex in cardiac regulation and the potential for severe cardiac consequences following neurological or psychiatric insults to this region.
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May warrant cardiac monitoring after insular insults; challenges orthodox autonomic models and leaves targeted interventions open.
Oppenheimer et al. (2016) conducted a review in Cardiac regulation and insular cortex dysfunction. The insular cortex plays a pivotal role in regulating cardiac function and autonomic responses, and its derangement can lead to serious consequences including sudden cardiac death.
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