Key result
Advanced speckle-tracking echocardiography identifies PICM in a leadless pacemaker patient, guiding successful CRT-P conversion.
Why the study?
Leadless pacemakers avoid certain transvenous pacemaker complications, but some persist, and the role of advanced speckle-tracking echocardiography in diagnosing leadless pacemaker-induced cardiomyopathy needed to be highlighted.
Can advanced speckle-tracking echocardiography diagnose pacing-induced cardiomyopathy associated with a leadless pacemaker?
Case Report (n=1)
Can advanced speckle-tracking echocardiography diagnose pacing-induced cardiomyopathy associated with a leadless pacemaker?
Advanced speckle-tracking echocardiography is valuable for identifying pacing-induced cardiomyopathy from leadless pacemakers and guiding the upgrade to cardiac resynchronization therapy.
May support speckle-tracking echocardiography for detecting leadless pacemaker cardiomyopathy; hypothesis-generating and requires prospective validation.
Background: A leadless pacemaker (LP) is a modern alternative to a transvenous pacemaker, allowing certain complications to be avoided; however, some cannot be eliminated. Aim: To highlight the essential role of advanced speckle-tracking echocardiography (STE) in diagnosing pacing-induced cardiomyopathy (PICM) caused by an LP. Clinical case: A 79-year-old male, after LP implantation a year earlier, was admitted due to heart failure (HF). Left ventricular ejection fraction (LVEF) was 40%, global longitudinal strain (GLS) was −10%, and interventricular mechanical delay (IVMD) was 42 ms. All these parameters were significantly better before the operation. Myocardial work indices confirmed dyssynchrony due to the right ventricular (RV) stimulation pattern, and PICM was considered. To verify the impact of RV pacing on the LV, measurements were taken after restoring the native rhythm, showing an improvement in LVEF (45%), GLS (−13%), IVMD (7 ms), and myocardial work indices. After the next HF exacerbation with further deterioration of the LV function, a decision to convert the LP to a standard CRT-P system was made, with immediate relief in clinical symptoms and improved echocardiographic parameters. Conclusions: This case highlights the essential role of STE echocardiography in identifying the detrimental impact of RV pacing, diagnosing PICM, and selecting the appropriate treatment for patients with LPs.
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Wabich et al. (2024) conducted a case report in Pacing-induced cardiomyopathy (PICM) associated with a leadless pacemaker (n=1). Advanced speckle-tracking echocardiography (STE) and conversion to CRT-P was evaluated on Diagnosis of pacing-induced cardiomyopathy and improvement in echocardiographic parameters. Advanced speckle-tracking echocardiography successfully identified pacing-induced cardiomyopathy in a patient with a leadless pacemaker, guiding successful conversion to a CRT-P system.
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