January 1, 1990Neurology
The Lewy body variant of Alzheimer's disease
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Discussion
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Implication
Randomized trial identifies distinct clinical features of Lewy body variant in Alzheimer's patients, highlighting diagnostic potential.
Key Points
- To investigate the clinical and neuropathological characteristics of the Lewy body variant of Alzheimer's disease.
- Included 36 Alzheimer's disease patients, with 13 diagnosed with Lewy body variant.
- Conducted neuropsychological tests on 9 LBV subjects and 9 matched AD patients.
- Performed neurologic examinations to assess symptoms such as bradykinesia and tremor.
- LBV patients exhibited greater neuron loss in specific brain areas compared to pure AD patients.
- Neuropsychological testing revealed significant deficits in attention and visuospatial processing in the LBV group.
- Increased incidence of masked facies and mild rigidity were observed in LBV patients.
Cite This Study
Hansen et al. (1990) studied this question.