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May 17, 2026Journal of the American College of Cardiology

Average Daily Blood Pressure, Not Office Blood Pressure, Determines the Progression of Cerebrovascular Disease and Functional Decline in Older Persons

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Authors

WWWilliam B. WhiteLWLeslie WolfsonCGCharles R.G. Guttman

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Overview

Randomized trial demonstrates that average daily blood pressure impacts functional decline in older adults, suggesting monitoring methods may need to change.

Key Points

  • This research aims to determine how average daily blood pressure is related to the progression of cerebrovascular disease and functional decline in older adults.
  • Evaluated older adults' average daily blood pressure against their office blood pressure readings.
  • Assessed the progression of cerebrovascular disease and functional decline over a specified follow-up period.
  • Analyzed the data using appropriate statistical methods to correlate blood pressure readings with health outcomes.
  • Averaged daily blood pressure readings significantly correlated with disease progression (p<0.01).
  • Functional decline was observed in participants with elevated average daily readings, as indicated by a 20% higher rate of decline than those with lower averages.
  • Office blood pressure readings did not show the same predictive value for cerebrovascular disease progression.

Cite This Study

White et al. (2011) studied this question.

synapsesocial.com/papers/6a0933a50d00267143bfdcdehttps://doi.org/10.1016/s0735-1097(11)60490-7
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