Key result
A combined laser-electrode catheter successfully created advanced AV block in 94% (16 of 17) of dogs, with persistent block and no septal perforation during 1-24 weeks of follow-up.
Why the study?
Does a combined laser-electrode catheter safely produce advanced AV block in a canine model?
Population
17 dogs (in vivo model)
Design
Preclinical
Follow-up
1-24 weeks (chronic study)
Authors
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Hypothesis-generating in canines; leaves open translation to human AV nodal ablation.
Does a combined laser-electrode catheter safely produce advanced AV block in a canine model?
A combined laser-electrode catheter safely and effectively produces advanced AV block in a canine model, demonstrating its potential utility for arrhythmia ablation.
Curtis et al. (1994) studied Atrioventricular conduction modification (animal model) (n=17). Combined laser-electrode catheter (continuous-wave Nd:YAG laser) was evaluated on Creation of advanced AV block. A combined laser-electrode catheter successfully created advanced AV block in 94% (16 of 17) of dogs, with persistent block and no septal perforation during 1-24 weeks of follow-up.
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