September 1, 1990Circulation

Modification of human atrioventricular nodal function by selective atrioventricular nodal artery catheterization.

View Full Paper

Ask AI

Bookmark

Why the study?

Does selective AV nodal artery catheterization with drug infusion modify human atrioventricular nodal function in subjects undergoing cardiac catheterization?

Population

8 subjects referred for diagnostic cardiac catheterization or electrophysiological studies, including 3 with…

Comparison

Selective AV nodal artery catheterization with… vs Control state and selective saline infusion at…

Design

Case_series

Authors

PWPAUL J. WANGTufts Medical Center GSGUILLERMO SOSA‐SUAREZSt Peter's Hospital PFPeter L. FriedmanElectrophysiology

Discussion

Member takes

Implication

Selective AV nodal artery drug delivery may modulate nodal properties in humans; hypothesis-generating for refractory SVT therapies.

Structured PICO

Does selective AV nodal artery catheterization with drug infusion modify human atrioventricular nodal function in subjects undergoing cardiac catheterization?

Population

8 subjects referred for diagnostic cardiac catheterization or electrophysiological studies, including 3 with no history of arrhythmias, 3 with SVT due to AVNRT, 1 with SVT due to AVRT-CBT, and 1 with nonsustained ventricular tachycardia.

Intervention

Selective AV nodal artery catheterization with constant infusion of 0.1 mg/min procainamide (n=1) or 50 micrograms/min acetylcholine (n=4).

Comparator

Control state (baseline) and selective saline infusion at identical rates.

Outcome

Electrophysiological parameters including sinus cycle length, AH interval, HV interval, AV nodal effective refractory period (AVN-ERP), and Wenckebach paced cycle length.surrogate

Selective AV nodal artery catheterization allows for targeted modulation of AV nodal function, potentially offering a novel delivery method for ablative agents in refractory SVT.

Cite This Study

WANG et al. (1990) studied this question.

synapsesocial.com/papers/6a0934cfb7dd28a06e160e99 https://doi.org/10.1161/01.cir.82.3.817

View Full Paper

Ask AI

Bookmark

Modification of human atrioventricular nodal function by selective atrioventricular nodal artery catheterization.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Modification of human atrioventricular nodal function by selective atrioventricular nodal artery catheterization.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider