What does this research mean for the field?

Sulfamoyl fluorides (RNHSO2F) can serve as versatile fluorosulfonamide radical precursors to enable diverse chemical transformations, expanding the previously narrow range of applicable radical types. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to explore the role of sulfamoyl fluorides as precursors in radical transformations and their broader applications.

May 17, 2026Organic Letters0 citations

Diverse Transformations Involving Sulfamoyl Fluorides (RNHSO 2 F) as Fluorosulfonamide Radical Precursors

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XZXi ZhangGeneral Cardiology HLHeyin LiCollaborative Innovation Center of Advanced Microstructures ZWZhen WangCollaborative Innovation Center of Advanced Microstructures

Key Points

This research aims to explore the role of sulfamoyl fluorides as precursors in radical transformations and their broader applications.
Investigated the synthesis of sulfamoyl fluorides through radical fluorosulfonamidation.
Analyzed the limitations regarding the range of radical types available.
Explored the significance of diverse transformations in chemical applications.
The study highlights the successful synthesis of sulfamoyl fluorides via radical methods.
It identifies the restricted range of radical types as a challenge for broader application.
Proposes potential pathways to enhance the utility of sulfamoyl fluorides in future studies.

Abstract

Sulfamoyl fluorides play a significant role in click chemistry. Notably, the synthesis of sulfamoyl fluorides via a radical fluorosulfonamidation process has attracted widespread interest. However, the narrow range of radical types has hindered further application of NSO

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Diverse Transformations Involving Sulfamoyl Fluorides (RNHSO 2 F) as Fluorosulfonamide Radical Precursors

Key Points

Abstract

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