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May 17, 2026RSC Medicinal ChemistryOpen Access

Structure-activity relationship for calanthoside, a potential hairgrowth stimulant with an indole 2- S -,3- O -bis-glucoside structure. Part 1: Role of two glucoside moieties in promoting HFDPC proliferation

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Authors

RSRiko SuzukiKTKatsuki TakashimaYMYoshiaki Mannse

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Overview

Randomized trial investigates the role of glucosides in promoting HFDPC proliferation for hair growth.

Key Points

  • This research aims to evaluate the structure-activity relationship of calanthoside and its effects on HFDPC proliferation.
  • Analyzed the effects of two glucoside moieties on hair follicle dermal papilla cells (HFDPC).
  • Conducted in vitro tests to assess proliferation rates after treatment with calanthoside.
  • Calanthoside significantly increased HFDPC proliferation compared to controls, with a notable enhancement observed with specific glucoside structures.

Cite This Study

Suzuki et al. (2026) studied this question.

synapsesocial.com/papers/6a095b1b7880e6d24efe0e87https://doi.org/10.1039/d6md00273k
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